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WATER STRUCTURE OF A HYDROPHOBIC PROTEIN AT ATOMIC RESOLUTION. PENTAGON RINGS OF WATER MOLECULES IN CRYSTALS OF CRAMBIN
Molecular functions: (select from list to view only structures with selected function)
Defense response
Extracellular region
1981-07-28
48
85655
399
Order structure laser-etched in crystal
High resolution crystal structure of human B2-adrenergic G protein-coupled receptor
Molecular functions: (select from list to view only structures with selected function)
Activation of adenylate cyclase activity
Activation of adenylate cyclase activity by G-protein signaling pathwa
Activation of transmembrane receptor protein tyrosine kinase activity
Adenylate cyclase binding
Adrenoceptor activity
Apical plasma membrane
Axon
Beta2-adrenergic receptor activity
Bone resorption
Brown fat cell differentiation
Caveola
Cell surface receptor linked signal transduction
Dendrite
Desensitization of G-protein coupled receptor protein signaling pathwa
Diet induced thermogenesis
Drug binding
Endosome
Endosome to lysosome transport
G-protein coupled receptor activity
G-protein coupled receptor protein signaling pathway
G-protein signaling, coupled to cAMP nucleotide second messenger
Heat generation
Integral to membrane
Integral to plasma membrane
Intracellular part
Lysosome
Membrane
Membrane fraction
Negative regulation of calcium ion transport via voltage-gated calcium
Negative regulation of inflammatory response
Negative regulation of multicellular organism growth
Negative regulation of ossification
Negative regulation of smooth muscle contraction
Norepinephrine binding
Nucleus
Plasma membrane
Positive regulation of apoptosis
Positive regulation of bone mineralization
Positive regulation of cell proliferation
Positive regulation of heart contraction
Positive regulation of MAPKKK cascade
Positive regulation of skeletal muscle growth
Positive regulation of transcription from RNA polymerase II promoter
Positive regulation of vasodilation
Potassium channel regulator activity
Protein binding
Protein complex binding
Protein homodimerization activity
Receptor activity
Receptor complex
Receptor-mediated endocytosis
Regulation of sensory perception of pain
Regulation of sodium ion transport
Regulation of systemic arterial blood pressure by norepinephrine-epine
Response to cold
Sarcolemma
Signal transducer activity
Signal transduction
Vasodilation by norepinephrine-epinephrine involved in regulation of s
2007-10-30
111
52528
1807
Order structure laser-etched in crystal
REFINEMENT OF AN ENZYME COMPLEX WITH INHIBITOR BOUND AT PARTIAL OCCUPANCY. HEN EGG-WHITE LYSOZYME AND TRI-N-ACETYLCHITOTRIOSE AT 1.75 ANGSTROMS RESOLUTION
Molecular functions: (select from list to view only structures with selected function)
Catalytic activity
Cell wall macromolecule catabolic process
Cytolysis
Defense response to bacterium
Hydrolase activity
Hydrolase activity, acting on glycosyl bonds
Lysozyme activity
Metabolic process
1994-01-31
28
52348
189
Order structure laser-etched in crystal
NMR STRUCTURE OF HUMAN INSULIN MUTANT HIS-B10-ASP, VAL-B12-ALA, PRO-B28-LYS, LYS-B29-PRO, 15 STRUCTURES
Molecular functions: (select from list to view only structures with selected function)
Activation of protein kinase B activity
Acute-phase response
Alpha-beta T cell activation
Carbohydrate metabolic process
Cell death
Cell-cell signaling
Centrosome
Extracellular region
Extracellular space
Fatty acid homeostasis
G-protein coupled receptor protein signaling pathway
Glucose homeostasis
Glucose metabolic process
Glucose transport
Hormone activity
Insulin receptor binding
Insulin-like growth factor binding
Insulin-like growth factor receptor binding
MAPKKK cascade
Negative regulation of acute inflammatory response
Negative regulation of apoptosis
Negative regulation of fatty acid metabolic process
Negative regulation of gluconeogenesis
Negative regulation of glycogen catabolic process
Negative regulation of lipid catabolic process
Negative regulation of NAD(P)H oxidase activity
Negative regulation of protein catabolic process
Negative regulation of protein kinase activity
Negative regulation of protein secretion
Negative regulation of proteolysis
Negative regulation of respiratory burst during acute inflammatory res
Negative regulation of vasodilation
Positive regulation of cell differentiation
Positive regulation of cell growth
Positive regulation of cell migration
Positive regulation of cell proliferation
Positive regulation of cellular protein metabolic process
Positive regulation of cytokine secretion
Positive regulation of DNA replication
Positive regulation of glucose import
Positive regulation of glycogen biosynthetic process
Positive regulation of glycolysis
Positive regulation of insulin receptor signaling pathway
Positive regulation of lipid biosynthetic process
Positive regulation of MAPKKK cascade
Positive regulation of mitosis
Positive regulation of nitric oxide biosynthetic process
Positive regulation of nitric-oxide synthase activity
Positive regulation of peptidyl-tyrosine phosphorylation
Positive regulation of phosphoinositide 3-kinase cascade
Positive regulation of protein amino acid autophosphorylation
Positive regulation of protein kinase B signaling cascade
Positive regulation of respiratory burst
Positive regulation of vasodilation
Protein binding
Regulation of cellular amino acid metabolic process
Regulation of establishment of protein localization
Regulation of gene-specific transcription
Regulation of protein localization
Regulation of protein secretion
Regulation of transmembrane transporter activity
Respiratory burst
Wound healing
2004-08-10
22
49203
230
Order structure laser-etched in crystal
THE CRYSTAL STRUCTURE OF HUMAN DEOXYHAEMOGLOBIN AT 1.74 ANGSTROMS RESOLUTION
Molecular functions: (select from list to view only structures with selected function)
Cytosolic small ribosomal subunit
Heme binding
Hemoglobin binding
Hemoglobin complex
Iron ion binding
Metal ion binding
Nitric oxide transport
Oxygen binding
Oxygen transport
Oxygen transporter activity
Positive regulation of nitric oxide biosynthetic process
Protein binding
Regulation of blood pressure
Regulation of blood vessel size
Transport
1984-07-17
152
47531
740
Order structure laser-etched in crystal
Crystal structure of E51C/E54C Psaz from A.faecalis with CLaNP probe
Molecular functions: (select from list to view only structures with selected function)
Copper ion binding
Electron carrier activity
Electron transport chain
Metal ion binding
Periplasmic space
Transport
2004-12-07
3
47338
31
Order structure laser-etched in crystal
GREEN FLUORESCENT PROTEIN FROM AEQUOREA VICTORIA
Molecular functions: (select from list to view only structures with selected function)
Bioluminescence
Cellular_component
Generation of precursor metabolites and energy
Molecular_function
Protein-chromophore linkage
1996-11-08
280
41328
1629
Order structure laser-etched in crystal
CRYSTAL STRUCTURE OF BOVINE RHODOPSIN
Molecular functions: (select from list to view only structures with selected function)
Detection of light stimulus
G-protein coupled receptor activity
G-protein coupled receptor protein signaling pathway
Integral to membrane
Membrane
Photoreceptor activity
Photoreceptor outer segment
Phototransduction
Protein amino acid phosphorylation
Protein-chromophore linkage
Receptor activity
Response to light stimulus
Response to stimulus
Sensory perception of light stimulus
Signal transducer activity
Signal transduction
Visual perception
2000-08-04
642
39441
4172
Order structure laser-etched in crystal
POTASSIUM CHANNEL (KCSA) FROM STREPTOMYCES LIVIDANS
Molecular functions: (select from list to view only structures with selected function)
Integral to membrane
Ion channel activity
Ion transport
Membrane
Plasma membrane
Potassium ion transport
Transport
Voltage-gated ion channel activity
Voltage-gated potassium channel activity
Voltage-gated potassium channel complex
1998-07-29
1118
39249
6599
Order structure laser-etched in crystal
DNA RECOGNITION BY GAL4: STRUCTURE OF A PROTEIN/DNA COMPLEX
Molecular functions: (select from list to view only structures with selected function)
Carbohydrate metabolic process
DNA binding
Galactose metabolic process
Metal ion binding
Nucleus
Positive regulation of transcription by galactose
Regulation of transcription, DNA-dependent
Sequence-specific DNA binding
Transcription
Transcription activator activity
Transcription factor activity
Zinc ion binding
1992-03-06
211
37930
974
Order structure laser-etched in crystal
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Top Scientists
MACKINNON, R.
PAVLETICH, N.P.
SIGLER, P.B.
HARRISON, S.C.
WILEY, D.C.
JEFFREY, P.D.
KURIYAN, J.
CLEMONS JR., W.M.
RAMAKRISHNAN, V.
STEITZ, T.A.
Top Functionality
Photosystem II
Thylakoid membrane
Photosystem II reaction center
Photosynthesis
Estrogen response element binding
Positive regulation of retinoic acid receptor signaling pathway
Thylakoid
Chromatin remodeling complex
Estrogen receptor activity
Estrogen receptor signaling pathway