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Results 1 to 10

Restricting to entries with function: Estrogen receptor activity

Sorted by: total score

Molecule	Release date	Citations	Downloads	Final score	Order crystal
HUMAN ESTROGEN RECEPTOR LIGAND-BINDING DOMAIN IN COMPLEX WITH 17BETA-ESTRADIOL	Molecular functions: (select from list to view only structures with selected function) Chromatin remodeling complexCytoplasmDNA bindingEstrogen receptor activityEstrogen receptor signaling pathwayEstrogen response element bindingLigand-dependent nuclear receptor activityLipid bindingMembraneMetal ion bindingNitric-oxide synthase regulator activityNucleolusNucleusPlasma membranePositive regulation of retinoic acid receptor signaling pathwayProtein bindingProtein N-terminus bindingReceptor activityRegulation of transcription, DNA-dependentSequence-specific DNA bindingSignal transductionSteroid bindingSteroid hormone receptor activityTranscriptionTranscription factor activityTranscription, DNA-dependentZinc ion binding
	1998-09-16	416	18312	1152	Order structure laser-etched in crystal
HUMAN ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH 4-HYDROXYTAMOXIFEN	Molecular functions: (select from list to view only structures with selected function) Chromatin remodeling complexCytoplasmDNA bindingEstrogen receptor activityEstrogen receptor signaling pathwayEstrogen response element bindingLigand-dependent nuclear receptor activityLipid bindingMembraneMetal ion bindingNitric-oxide synthase regulator activityNucleolusNucleusPlasma membranePositive regulation of retinoic acid receptor signaling pathwayProtein bindingProtein N-terminus bindingReceptor activityRegulation of transcription, DNA-dependentSequence-specific DNA bindingSignal transductionSteroid bindingSteroid hormone receptor activityTranscriptionTranscription factor activityTranscription, DNA-dependentZinc ion binding
	1999-04-08	323	19170	959	Order structure laser-etched in crystal
HUMAN ESTROGEN RECEPTOR LIGAND-BINDING DOMAIN IN COMPLEX WITH RALOXIFENE	Molecular functions: (select from list to view only structures with selected function) Chromatin remodeling complexCytoplasmDNA bindingEstrogen receptor activityEstrogen receptor signaling pathwayEstrogen response element bindingLigand-dependent nuclear receptor activityLipid bindingMembraneMetal ion bindingNitric-oxide synthase regulator activityNucleolusNucleusPlasma membranePositive regulation of retinoic acid receptor signaling pathwayProtein bindingProtein N-terminus bindingReceptor activityRegulation of transcription, DNA-dependentSequence-specific DNA bindingSignal transductionSteroid bindingSteroid hormone receptor activityTranscriptionTranscription factor activityTranscription, DNA-dependentZinc ion binding
	1998-09-16	416	15110	951	Order structure laser-etched in crystal
HUMAN ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH DIETHYLSTILBESTROL AND A GLUCOCORTICOID RECEPTOR INTERACTING PROTEIN 1 NR BOX II PEPTIDE	Molecular functions: (select from list to view only structures with selected function) Chromatin remodeling complexCytoplasmDNA bindingEstrogen receptor activityEstrogen receptor signaling pathwayEstrogen response element bindingLigand-dependent nuclear receptor activityLipid bindingMembraneMetal ion bindingNitric-oxide synthase regulator activityNucleolusNucleusPlasma membranePositive regulation of retinoic acid receptor signaling pathwayProtein bindingProtein N-terminus bindingReceptor activityRegulation of transcription, DNA-dependentSequence-specific DNA bindingSignal transductionSteroid bindingSteroid hormone receptor activityTranscriptionTranscription factor activityTranscription, DNA-dependentZinc ion binding
	1999-04-08	323	14891	745	Order structure laser-etched in crystal
THE CRYSTAL STRUCTURE OF THE ESTROGEN RECEPTOR DNA-BINDING DOMAIN BOUND TO DNA: HOW RECEPTORS DISCRIMINATE BETWEEN THEIR RESPONSE ELEMENTS	Molecular functions: (select from list to view only structures with selected function) Chromatin remodeling complexCytoplasmDNA bindingEstrogen receptor activityEstrogen receptor signaling pathwayEstrogen response element bindingLigand-dependent nuclear receptor activityLipid bindingMembraneMetal ion bindingNitric-oxide synthase regulator activityNucleolusNucleusPlasma membranePositive regulation of retinoic acid receptor signaling pathwayProtein bindingProtein N-terminus bindingReceptor activityRegulation of transcription, DNA-dependentSequence-specific DNA bindingSignal transductionSteroid bindingSteroid hormone receptor activityTranscriptionTranscription factor activityTranscription, DNA-dependentZinc ion binding
	1995-11-23	136	16117	299	Order structure laser-etched in crystal
HUMAN OESTROGEN RECEPTOR BETA LIGAND-BINDING DOMAIN IN COMPLEX WITH PARTIAL AGONIST GENISTEIN	Molecular functions: (select from list to view only structures with selected function) Cell-cell signalingDNA bindingEstrogen receptor activityEstrogen receptor signaling pathwayLigand-dependent nuclear receptor activityLipid bindingMetal ion bindingMitochondrionNegative regulation of cell growthNucleusProtein bindingReceptor activityReceptor antagonist activityRegulation of transcription, DNA-dependentSequence-specific DNA bindingSignal transductionSteroid bindingSteroid hormone receptor activityTranscriptionTranscription coactivator activityTranscription factor activityZinc ion binding
	2000-07-28	108	12569	224	Order structure laser-etched in crystal
ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN COMPLEXED TO ESTRADIOL	Molecular functions: (select from list to view only structures with selected function) Chromatin remodeling complexCytoplasmDNA bindingEstrogen receptor activityEstrogen receptor signaling pathwayEstrogen response element bindingLigand-dependent nuclear receptor activityLipid bindingMembraneMetal ion bindingNitric-oxide synthase regulator activityNucleolusNucleusPlasma membranePositive regulation of retinoic acid receptor signaling pathwayProtein bindingProtein N-terminus bindingReceptor activityRegulation of transcription, DNA-dependentSequence-specific DNA bindingSignal transductionSteroid bindingSteroid hormone receptor activityTranscriptionTranscription factor activityTranscription, DNA-dependentZinc ion binding
	1998-09-16	65	20093	198	Order structure laser-etched in crystal
RAT OESTROGEN RECEPTOR BETA LIGAND-BINDING DOMAIN IN COMPLEX WITH ANTAGONIST RALOXIFENE	Molecular functions: (select from list to view only structures with selected function) Behavioral fear responseCytoplasmDNA bindingEstrogen receptor activityEstrogen receptor signaling pathwayHormone bindingLearning or memoryLigand-dependent nuclear receptor activityLipid bindingMetal ion bindingMitochondrionNegative regulation of behaviorNegative regulation of epithelial cell proliferationNeuron projectionNeuroprotectionNucleusPerikaryonPositive regulation of gene-specific transcriptionPositive regulation of survival gene product expressionPositive regulation of transcription from RNA polymerase II promoterReceptor activityRegulation of transcription, DNA-dependentResponse to testosterone stimulusSequence-specific DNA bindingSteroid bindingSteroid hormone receptor activityTranscriptionTranscription factor activityTranscription regulator activityZinc ion binding
	2000-07-28	108	9816	175	Order structure laser-etched in crystal
Human Estrogen Receptor alpha Ligand-binding Domain in Complex with (R,R)-5,11-cis-diethyl-5,6,11,12-tetrahydrochrysene-2,8-diol and a Glucocorticoid Receptor Interacting Protein 1 NR box II Peptide	Molecular functions: (select from list to view only structures with selected function) Chromatin remodeling complexCytoplasmDNA bindingEstrogen receptor activityEstrogen receptor signaling pathwayEstrogen response element bindingLigand-dependent nuclear receptor activityLigand-dependent nuclear receptor transcription coactivator activityLipid bindingMembraneMetal ion bindingNegative regulation of transcription from RNA polymerase II promoterNitric-oxide synthase regulator activityNuclear hormone receptor bindingNucleolusNucleusPlasma membranePositive regulation of retinoic acid receptor signaling pathwayPositive regulation of transcription from RNA polymerase II promoterProtein bindingProtein N-terminus bindingReceptor activityReceptor bindingRegulation of transcriptionRegulation of transcription, DNA-dependentSequence-specific DNA bindingSignal transducer activitySignal transductionSteroid bindingSteroid hormone receptor activityThyroid hormone receptor coactivator activityTranscriptionTranscription coactivator activityTranscription factor activityTranscription regulator activityTranscription repressor activityTranscription, DNA-dependentZinc ion binding
	2002-05-01	31	12717	72	Order structure laser-etched in crystal
Human Estrogen Receptor beta Ligand-binding Domain in Complex with (R,R)-5,11-cis-diethyl-5,6,11,12-tetrahydrochrysene-2,8-diol	Molecular functions: (select from list to view only structures with selected function) Cell-cell signalingDNA bindingEstrogen receptor activityEstrogen receptor signaling pathwayLigand-dependent nuclear receptor activityLipid bindingMetal ion bindingMitochondrionNegative regulation of cell growthNucleusProtein bindingReceptor activityReceptor antagonist activityRegulation of transcription, DNA-dependentSequence-specific DNA bindingSignal transductionSteroid bindingSteroid hormone receptor activityTranscriptionTranscription coactivator activityTranscription factor activityZinc ion binding
	2002-05-01	31	11427	65	Order structure laser-etched in crystal

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• Top Scientists

  1. MACKINNON, R.
  2. PAVLETICH, N.P.
  3. SIGLER, P.B.
  4. HARRISON, S.C.
  5. WILEY, D.C.
  6. JEFFREY, P.D.
  7. KURIYAN, J.
  8. CLEMONS JR., W.M.
  9. RAMAKRISHNAN, V.
  10. STEITZ, T.A.

• Top Functionality

  1. Photosystem II
  2. Thylakoid membrane
  3. Photosystem II reaction center
  4. Photosynthesis
  5. Estrogen response element binding
  6. Positive regulation of retinoic acid receptor signaling pathway
  7. Thylakoid
  8. Chromatin remodeling complex
  9. Estrogen receptor activity
  10. Estrogen receptor signaling pathway