Structural rankings

Results 1 to 10

Restricting to entries for author: SIGLER, P.B.

Sorted by: total score

Molecule	Release date	Citations	Downloads	Final score	Order crystal
CRYSTAL STRUCTURE OF THE ASYMMETRIC CHAPERONIN COMPLEX GROEL/GROES/(ADP)7	Molecular functions: (select from list to view only structures with selected function) ATP bindingCell cycleCell divisionCellular protein metabolic processCytoplasmCytosolIdentical protein bindingMembraneNucleotide bindingProtein bindingProtein foldingProtein refoldingUnfolded protein binding
	1997-10-15	228	22224	739	Order structure laser-etched in crystal
HETEROTRIMERIC COMPLEX OF A GT-ALPHA/GI-ALPHA CHIMERA AND THE GT-BETA-GAMMA SUBUNITS	Molecular functions: (select from list to view only structures with selected function) Activation of phospholipase C activity by G-protein coupled receptor pAcyl bindingCell proliferationDetection of light stimulus involved in visual perceptionEye photoreceptor cell developmentG-protein beta/gamma-subunit bindingG-protein coupled receptor protein signaling pathwayGDP bindingGTP bindingGuanyl nucleotide bindingHeterotrimeric G-protein complexMembraneNegative regulation of cyclic-nucleotide phosphodiesterase activityNucleotide bindingPhotoreceptor connecting ciliumPhotoreceptor outer segmentPhotoreceptor outer segment membranePhototransductionPlasma membraneProtein bindingProtein kinase bindingProtein localizationResponse to light stimulusResponse to stimulusSensory perception of tasteSensory perception of umami tasteSignal transducer activitySignal transductionVisual perception
	1997-03-12	309	16349	720	Order structure laser-etched in crystal
Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA	Molecular functions: (select from list to view only structures with selected function) Anti-apoptosisChromatin bindingChromatin modificationChromatin remodelingChromatin-mediated maintenance of transcriptionCytoplasmDNA bindingDouble-stranded DNA bindingGlucocorticoid receptor activityHeat shock protein bindingIdentical protein bindingLigand-dependent nuclear receptor activityLipid bindingMetal ion bindingNegative regulation of transforming growth factor beta receptor signalNF-kappaB bindingNucleusProtein bindingProtein complexProtein complex bindingProtein dimerization activityProtein heterodimerization activityProtein homodimerization activityProtein N-terminus bindingReceptor activityReceptor tyrosine kinase bindingRegulation of cell proliferationRegulation of transcription, DNA-dependentResponse to arsenicSequence-specific DNA bindingSteroid bindingSteroid hormone receptor activityTranscriptionTranscription activator activityTranscription factor activityTranscription from RNA polymerase II promoterZinc ion binding
	2003-10-21	324	10260	664	Order structure laser-etched in crystal
CRYSTAL STRUCTURE OF A YEAST TBP/TATA-BOX COMPLEX	Molecular functions: (select from list to view only structures with selected function) BindingChromatin bindingDNA bending activityDNA bindingGeneral RNA polymerase II transcription factor activityNucleoplasmNucleusProtein bindingProtein homodimerization activityRegulation of transcription, DNA-dependentRNA polymerase I transcription factor activityRNA polymerase I transcription factor complexRNA polymerase II transcription factor activityRNA polymerase III transcription factor activitySequence-specific DNA bindingTranscriptionTranscription factor TFIID complexTranscription factor TFIIIB complexTranscription from RNA polymerase I promoterTranscription from RNA polymerase II promoterTranscription from RNA polymerase III promoterTranscription initiation from RNA polymerase II promoterTranscription initiation from RNA polymerase III promoter
	1995-01-26	365	13392	648	Order structure laser-etched in crystal
Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA	Molecular functions: (select from list to view only structures with selected function) Anti-apoptosisChromatin bindingChromatin modificationChromatin remodelingChromatin-mediated maintenance of transcriptionCytoplasmDNA bindingDouble-stranded DNA bindingGlucocorticoid receptor activityHeat shock protein bindingIdentical protein bindingLigand-dependent nuclear receptor activityLipid bindingMetal ion bindingNegative regulation of transforming growth factor beta receptor signalNF-kappaB bindingNucleusProtein bindingProtein complexProtein complex bindingProtein dimerization activityProtein heterodimerization activityProtein homodimerization activityProtein N-terminus bindingReceptor activityReceptor tyrosine kinase bindingRegulation of cell proliferationRegulation of transcription, DNA-dependentResponse to arsenicSequence-specific DNA bindingSteroid bindingSteroid hormone receptor activityTranscriptionTranscription activator activityTranscription factor activityTranscription from RNA polymerase II promoterZinc ion binding
	2003-10-28	324	9662	626	Order structure laser-etched in crystal
THE CRYSTAL STRUCTURE OF THE BACTERIAL CHAPERONIN GROEL AT 2.8 ANGSTROMS	Molecular functions: (select from list to view only structures with selected function) ATP bindingCell cycleCell divisionCellular protein metabolic processCytoplasmCytosolIdentical protein bindingMembraneNucleotide bindingProtein bindingProtein foldingProtein refoldingUnfolded protein binding
	1995-10-15	308	10988	459	Order structure laser-etched in crystal
CRYSTALLOGRAPHIC ANALYSIS OF THE INTERACTION OF THE GLUCOCORTICOID RECEPTOR WITH DNA	Molecular functions: (select from list to view only structures with selected function) Anti-apoptosisChromatin bindingChromatin modificationChromatin remodelingChromatin-mediated maintenance of transcriptionCytoplasmDNA bindingDouble-stranded DNA bindingGlucocorticoid receptor activityHeat shock protein bindingIdentical protein bindingLigand-dependent nuclear receptor activityLipid bindingMetal ion bindingNegative regulation of transforming growth factor beta receptor signalNF-kappaB bindingNucleusProtein bindingProtein complexProtein complex bindingProtein dimerization activityProtein heterodimerization activityProtein homodimerization activityProtein N-terminus bindingReceptor activityReceptor tyrosine kinase bindingRegulation of cell proliferationRegulation of transcription, DNA-dependentResponse to arsenicSequence-specific DNA bindingSteroid bindingSteroid hormone receptor activityTranscriptionTranscription activator activityTranscription factor activityTranscription from RNA polymerase II promoterZinc ion binding
	1994-01-31	324	10728	447	Order structure laser-etched in crystal
CRYSTAL STRUCTURE OF TRP REPRESSOR OPERATOR COMPLEX AT ATOMIC RESOLUTION	Molecular functions: (select from list to view only structures with selected function) CytoplasmDNA bindingIntracellularNegative regulation of transcription, DNA-dependentRegulation of transcription, DNA-dependentSequence-specific DNA bindingTranscriptionTranscription factor activityTranscription repressor activity
	1994-01-31	256	12364	407	Order structure laser-etched in crystal
BETA-GAMMA DIMER OF THE HETEROTRIMERIC G-PROTEIN TRANSDUCIN	Molecular functions: (select from list to view only structures with selected function) Activation of phospholipase C activity by G-protein coupled receptor pCell proliferationEye photoreceptor cell developmentG-protein coupled receptor protein signaling pathwayHeterotrimeric G-protein complexMembranePhotoreceptor outer segmentPhototransductionPlasma membraneProtein localizationSensory perception of tasteSignal transducer activitySignal transduction
	1997-04-01	244	11074	386	Order structure laser-etched in crystal
HORMONE-BOUND HUMAN PROGESTERONE RECEPTOR LIGAND-BINDING DOMAIN	Molecular functions: (select from list to view only structures with selected function) Cell-cell signalingDNA bindingEpithelial cell maturationIntracellular membrane-bounded organelleLigand-dependent nuclear receptor activityLipid bindingMammary gland developmentMetal ion bindingNucleusOvulation from ovarian follicleProgesterone receptor signaling pathwayProtein bindingProtein N-terminus bindingReceptor activityRegulation of epithelial cell proliferationRegulation of transcription, DNA-dependentSequence-specific DNA bindingSignal transductionSteroid bindingSteroid hormone receptor activityTranscriptionTranscription factor activityTranscription regulator activityZinc ion binding
	1998-07-15	108	19854	322	Order structure laser-etched in crystal

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• Top Scientists

  1. MACKINNON, R.
  2. PAVLETICH, N.P.
  3. SIGLER, P.B.
  4. HARRISON, S.C.
  5. WILEY, D.C.
  6. JEFFREY, P.D.
  7. KURIYAN, J.
  8. CLEMONS JR., W.M.
  9. RAMAKRISHNAN, V.
  10. STEITZ, T.A.

• Top Functionality

  1. Photosystem II
  2. Thylakoid membrane
  3. Photosystem II reaction center
  4. Photosynthesis
  5. Estrogen response element binding
  6. Positive regulation of retinoic acid receptor signaling pathway
  7. Thylakoid
  8. Chromatin remodeling complex
  9. Estrogen receptor activity
  10. Estrogen receptor signaling pathway